What it is
TB-500 is a lab-made peptide based on part of thymosin beta-4, a protein the body makes itself, studied in the lab for wound and tissue repair. It is not an approved drug for any animal.
What the research says
No clinical trial in cats has been published, so nobody can say whether it helps your cat, or what a safe amount would be.
It is not an approved animal drug. Vials sold for animals are usually labelled "research only", which means no one has taken responsibility for giving them to your cat. Ask your vet which tested treatments fit the problem.
The risks
- 1No clinical trial has tested safety in cats.
- 2Products aren't checked by the FDA, so the product may not contain what the label says.
- 3"Research only" labels mean there is no one to call if something goes wrong.
- 4Mixing and storing a vial at home is easy to get wrong.
Who sells it, ranked by proof
2 sellers sell TB-500 for cats. They’re ranked by what they prove, not by what they pay us. A seller with an FDA warning letter stays listed, with the letter under its name. Sellers label these products “for research”; we list them so you can see who proves what’s in the product.
PeptaGen
TB-500 · Vial
Peppets
TB-500 treats · Treats
Peppets
TB-500 vial · Vial
Compare the sellers · How we score sellers · How to read a lab test
Questions cat owners ask
Is TB-500 safe for cats?
Nobody knows. No clinical trial in cats has been published, and products aren't checked by the FDA. Talk to your vet before you try anything.
Does TB-500 work for cats?
Nobody can say. Without a clinical trial in cats, there is no good evidence that it helps any cat condition, or that it doesn't.
Is TB-500 legal for cats?
It is not an approved drug for animals. FDA treats a product sold to treat disease in animals without approval as an unapproved drug, and in November 2024 it warned six sellers of seizure products for dogs and cats on those grounds. We found no FDA action aimed at TB-500 for animals, which is not the same as approval. News in 2026 about compounding TB-500 concerns prescriptions for people. It is not an approval, and it does not cover animals.
Can my vet prescribe TB-500?
Not as an approved medicine, because none exists. Compounding for one animal is a separate route under FDA guidance, with conditions, and we found no vet compounding pharmacy offering it (checked October 2026). Ask your vet which approved options fit your cat.